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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIMS1 All Species: 4.55
Human Site: S474 Identified Species: 11.11
UniProt: Q86UR5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UR5 NP_055804.2 1692 189073 S474 Q E P L R K Q S R L D P S S A
Chimpanzee Pan troglodytes XP_001157433 1557 176218 S372 E R R H S D V S L A N A D L E
Rhesus Macaque Macaca mulatta NP_001032357 1028 115316
Dog Lupus familis XP_538998 1691 188872 Q473 A Q E P L R K Q S R L D P S S
Cat Felis silvestris
Mouse Mus musculus Q99NE5 1463 163143 E278 S Q Q A L G P E Q K Q A S R S
Rat Rattus norvegicus Q9JIR4 1615 179636 P418 R H S D V A L P H T E A A A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509917 1381 156408 P196 G S N R V Y E P P Q V V P R G
Chicken Gallus gallus XP_419884 1695 190353 S476 H D T F K K Q S R L D P S S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920695 1451 162180 D266 K K P P A A S D Q N G K P G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22366 1563 175460 N378 H V E D D G M N Q R P T F Y T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.2 60.2 94 N.A. 81.5 87.8 N.A. 47.4 87.6 N.A. 55.7 N.A. N.A. N.A. 21.1 N.A.
Protein Similarity: 100 70.5 60.3 96.3 N.A. 82.8 90 N.A. 58.4 92.4 N.A. 64.8 N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: 100 6.6 0 6.6 N.A. 6.6 6.6 N.A. 0 66.6 N.A. 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 20 0 33.3 N.A. 26.6 33.3 N.A. 6.6 80 N.A. 26.6 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 20 0 0 0 10 0 30 10 10 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 20 10 10 0 10 0 0 20 10 10 0 0 % D
% Glu: 10 10 20 0 0 0 10 10 0 0 10 0 0 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 10 0 0 0 0 20 0 0 0 0 10 0 0 10 10 % G
% His: 20 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 0 0 10 20 10 0 0 10 0 10 0 0 0 % K
% Leu: 0 0 0 10 20 0 10 0 10 20 10 0 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 10 0 10 10 0 0 0 0 % N
% Pro: 0 0 20 20 0 0 10 20 10 0 10 20 30 0 10 % P
% Gln: 10 20 10 0 0 0 20 10 30 10 10 0 0 0 0 % Q
% Arg: 10 10 10 10 10 10 0 0 20 20 0 0 0 20 0 % R
% Ser: 10 10 10 0 10 0 10 30 10 0 0 0 30 30 20 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 0 10 0 0 10 % T
% Val: 0 10 0 0 20 0 10 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _